Anti-EYA3 Polyclonal Antibody
品牌:solarbio | 货号:K005535P
| 英文名称 | Anti-EYA3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EYA3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 2140 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EYA3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EYA3 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q99504 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3′ UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. |