Anti-EYA3 Polyclonal Antibody
品牌:solarbio | 货号:K005535P
英文名称 |
Anti-EYA3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EYA3 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
63kDa |
Gene ID |
2140 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human EYA3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human EYA3 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q99504 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3′ UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. |