Anti-ANGPT1 Polyclonal Antibody
品牌：solarbio | 货号：K005523P
| 英文名称 | Anti-ANGPT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AGP1;AGPT;ANG1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 58kDa |
| Gene ID | 284 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANGPT1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANGPT1 |
| Subcellular Locations | Secreted |
| Swiss Prot | Q15389 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |