Anti-NFKB2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NFKB2 Polyclonal Antibody

品牌:solarbio | 货号:K003592P

英文名称 Anti-NFKB2 Polyclonal Antibody
宿主 Rabbit
别名 CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 97kDa
Gene ID 4791
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human NFKB2
性状 液体
Public Immunogen Range A synthetic peptide of human NFKB2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q00653
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.