Anti-NFKB2 Polyclonal Antibody
品牌:solarbio | 货号:K003592P
| 英文名称 | Anti-NFKB2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 97kDa |
| Gene ID | 4791 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NFKB2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NFKB2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q00653 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |