Anti-CD8 Monoclonal antibody-一抗-抗体-蛋白与免疫

Anti-CD8 Monoclonal antibody

品牌:solarbio | 货号:K006379M

英文名称 Anti-CD8 Monoclonal antibody
宿主 Mouse
别名 MAL;p32;Leu2;CD8A
应用 FCM
稀释比例 FCM 1:200-400.
交叉反应 Human
Gene ID 925
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant fragment of human CD8 expressed in E. Coli.
性状 液体
Public Immunogen Range Purified recombinant fragment of human CD8 expressed in E. Coli.
Subcellular Locations Membrane Secreted
Swiss Prot P01732
克隆号 RAVB3
克隆类型 Monoclonal antibody
背景资料 CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.