Anti-FBLN5 Polyclonal Antibody
品牌：solarbio | 货号：K006131P
| 英文名称 | Anti-FBLN5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADCL2;ARCL1A;ARMD3;DANCE;EVEC;FIBL-5;HNARMD;UP50 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 50kDa |
| Gene ID | 10516 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FBLN5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FBLN5 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | Q9UBX5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). |