Anti-LCP1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-LCP1 Polyclonal Antibody

品牌:solarbio | 货号:K004065P

英文名称 Anti-LCP1 Polyclonal Antibody
宿主 Rabbit
别名 CP64;HEL-S-37;L-PLASTIN;LC64P;LPL;PLS2
应用 WB IP
稀释比例 WB 1:500-2000. IP 1:20-50.
交叉反应 Human Mouse
蛋白分子量 70kDa
Gene ID 3936
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human LCP1
性状 液体
Public Immunogen Range Recombinant protein of human LCP1
Subcellular Locations Cell junction Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton ruffle membrane
Swiss Prot P13796
克隆类型 Polyclonal Antibody
背景资料 Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.