Anti-ALKBH2 Polyclonal Antibody
品牌：solarbio | 货号：K006863P
| 英文名称 | Anti-ALKBH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ABH2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 29kDa |
| Gene ID | 121642 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALKBH2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALKBH2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q6NS38 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. |