Anti-LPIN1 Polyclonal Antibody
品牌：solarbio | 货号：K008030P
| 英文名称 | Anti-LPIN1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PAP1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 99kDa |
| Gene ID | 23175 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human LPIN1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human LPIN1 |
| Subcellular Locations | Nucleus Membrane |
| Swiss Prot | Q14693 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. |