Anti-ELAC2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ELAC2 Polyclonal Antibody

品牌:solarbio | 货号:K005034P

英文名称 Anti-ELAC2 Polyclonal Antibody
宿主 Rabbit
别名 COXPD17;ELC2;HPC2
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
交叉反应 Human
蛋白分子量 92kDa
Gene ID 60528
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ELAC2
性状 液体
Public Immunogen Range Recombinant protein of human ELAC2
Subcellular Locations Mitochondrion Nucleus
Swiss Prot Q9BQ52
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.