Anti-DBI Polyclonal Antibody
品牌：solarbio | 货号：K003948P
| 英文名称 | Anti-DBI Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACBD1;ACBP;CCK-RP;EP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 10kDa |
| Gene ID | 1622 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DBI |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DBI |
| Subcellular Locations | Endoplasmic reticulum Golgi apparatus |
| Swiss Prot | P07108 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. |