Anti-TMED10 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TMED10 Polyclonal Antibody

品牌:solarbio | 货号:K004783P

英文名称 Anti-TMED10 Polyclonal Antibody
宿主 Rabbit
别名 P24(DELTA);S31I125;S31III125;TMP21;Tmp-21-I;p23;p24d1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 25kDa
Gene ID 10972
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TMED10
性状 液体
Public Immunogen Range Recombinant protein of human TMED10
Subcellular Locations Cell membrane Cytoplasmic vesicle Endoplasmic reticulum membrane Endoplasmic reticulum-Golgi intermediate compartment membrane Golgi apparatus Melanosome Single-pass type I membrane protein cis-Golgi network membrane secretory vesicle membrane trans-Golgi network membrane
Swiss Prot P49755
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex’s gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer’s disease. This gene has a pseudogene on chromosome 8.