Anti-TMED10 Polyclonal Antibody
品牌:solarbio | 货号:K004783P
英文名称 |
Anti-TMED10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
P24(DELTA);S31I125;S31III125;TMP21;Tmp-21-I;p23;p24d1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
25kDa |
Gene ID |
10972 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TMED10 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TMED10 |
Subcellular Locations |
Cell membrane Cytoplasmic vesicle Endoplasmic reticulum membrane Endoplasmic reticulum-Golgi intermediate compartment membrane Golgi apparatus Melanosome Single-pass type I membrane protein cis-Golgi network membrane secretory vesicle membrane trans-Golgi network membrane |
Swiss Prot |
P49755 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex’s gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer’s disease. This gene has a pseudogene on chromosome 8. |