Anti-POLD2 Polyclonal Antibody
品牌:solarbio | 货号:K004814P
英文名称 |
Anti-POLD2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
POLD2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
51kDa |
Gene ID |
5425 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human POLD2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human POLD2 |
Subcellular Locations |
Nucleus |
Swiss Prot |
P49005 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3′ to 5′ exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. |