Anti-CAPN10 Polyclonal Antibody
品牌:solarbio | 货号:K006092P
英文名称 |
Anti-CAPN10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CANP10;NIDDM1 |
应用 |
WB |
稀释比例 |
WB 1:1000-4000. |
交叉反应 |
Human |
蛋白分子量 |
75kDa |
Gene ID |
11132 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CAPN10 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CAPN10 |
Subcellular Locations |
Cytosol Mitochondrion Plasma Membrane |
Swiss Prot |
Q9HC96 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. |