Anti-ABCB11 Polyclonal Antibody
品牌:solarbio | 货号:K005859P
英文名称 |
Anti-ABCB11 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ABC16;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;SPGP |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
146kDa |
Gene ID |
8647 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ABCB11 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ABCB11 |
Subcellular Locations |
Membrane Multi-pass membrane protein |
Swiss Prot |
O95342 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |