Anti-ABCB11 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ABCB11 Polyclonal Antibody

品牌:solarbio | 货号:K005859P

英文名称 Anti-ABCB11 Polyclonal Antibody
宿主 Rabbit
别名 ABC16;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;SPGP
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 146kDa
Gene ID 8647
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ABCB11
性状 液体
Public Immunogen Range Recombinant protein of human ABCB11
Subcellular Locations Membrane Multi-pass membrane protein
Swiss Prot O95342
克隆类型 Polyclonal Antibody
背景资料 The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.