Anti-GDF15 Polyclonal Antibody
品牌:solarbio | 货号:K006750P
| 英文名称 | Anti-GDF15 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Growth/differentiation factor 15;GDF-15;MIC-1;MIC-1;NRG-1 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-5000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 34kDa |
| Gene ID | |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GDF15 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GDF15 |
| Subcellular Locations | Secreted |
| Swiss Prot | Q99988 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the emergency circuit that shapes feeding responses to stressful conditions. |