Anti-HSPB8 Polyclonal Antibody
品牌：solarbio | 货号：K006761P
| 英文名称 | Anti-HSPB8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | H11;HMN2;CMT2L;DHMN2;E2IG1;HMN2A;HSP22 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 26353 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HSPB8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HSPB8 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9UJY1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |