Anti-TRPM8 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TRPM8 Polyclonal Antibody

品牌:solarbio | 货号:K006331P

英文名称 Anti-TRPM8 Polyclonal Antibody
宿主 Rabbit
别名 LTRPC6;TRPP8
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 128kDa
Gene ID 79054
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TRPM8
性状 液体
Public Immunogen Range Recombinant protein of human TRPM8
Subcellular Locations Cell membrane Endoplasmic reticulum membrane Membrane raft Multi-pass membrane protein
Swiss Prot Q7Z2W7
克隆类型 Polyclonal Antibody
背景资料 Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves.