Anti-HSD17B2 Polyclonal Antibody
品牌：solarbio | 货号：K007065P
| 英文名称 | Anti-HSD17B2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HSD17;SDR9C2;EDH17B2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 43kDa |
| Gene ID | 3294 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HSD17B2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HSD17B2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P37059 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | 17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis. |