Anti-MVK Polyclonal Antibody
品牌:solarbio | 货号:K003933P
英文名称 |
Anti-MVK Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LRBP;MK;MVLK;POROK3 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
42kDa |
Gene ID |
4598 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MVK |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MVK |
Subcellular Locations |
Peroxisome |
Swiss Prot |
Q03426 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. |