Anti-TRPM5 Polyclonal Antibody
品牌：solarbio | 货号：K007636P
| 英文名称 | Anti-TRPM5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MTR1;LTRPC5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 131kDa |
| Gene ID | 29850 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TRPM5 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TRPM5 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9NZQ8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. |