Anti-CASP8AP2 Polyclonal Antibody
品牌:solarbio | 货号:K007707P
英文名称 |
Anti-CASP8AP2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CED-4;FLASH;RIP25 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
223kDa |
Gene ID |
9994 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CASP8AP2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CASP8AP2 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q9UKL3 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. |