Anti-CASP8AP2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CASP8AP2 Polyclonal Antibody

品牌:solarbio | 货号:K007707P

英文名称 Anti-CASP8AP2 Polyclonal Antibody
宿主 Rabbit
别名 CED-4;FLASH;RIP25
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 223kDa
Gene ID 9994
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CASP8AP2
性状 液体
Public Immunogen Range A synthetic peptide of human CASP8AP2
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q9UKL3
克隆类型 Polyclonal Antibody
背景资料 This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.