Anti-RNLS Polyclonal Antibody
品牌:solarbio | 货号:K007808P
英文名称 |
Anti-RNLS Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
C10orf59;RENALASE |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
38kDa |
Gene ID |
55328 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human RNLS |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human RNLS |
Swiss Prot |
Q5VYX0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform toform beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. |