Anti-HIST1H3A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HIST1H3A Polyclonal Antibody

品牌:solarbio | 货号:K007970P

英文名称 Anti-HIST1H3A Polyclonal Antibody
宿主 Rabbit
别名 H3/A;H3FA
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 15kDa
Gene ID 8290
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human HIST1H3A
性状 液体
Public Immunogen Range A synthetic peptide of human HIST1H3A
Subcellular Locations Nucleus
Swiss Prot P68431
克隆类型 Polyclonal Antibody
背景资料 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.