Anti-CNTNAP1 Polyclonal Antibody
品牌：solarbio | 货号：K007992P
| 英文名称 | Anti-CNTNAP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | P190;CASPR;NRXN4;CNTNAP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:20-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 156kDa |
| Gene ID | 8506 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CNTNAP1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CNTNAP1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P78357 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for ‘contactin-associated protein,’ includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. |