Anti-F7 Polyclonal Antibody
品牌:solarbio | 货号:K008248P
英文名称 |
Anti-F7 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
SPCA |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
49kDa |
Gene ID |
2155 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human F7 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human F7 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P08709 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |