Anti-ACAD11 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ACAD11 Polyclonal Antibody

品牌:solarbio | 货号:K008273P

英文名称 Anti-ACAD11 Polyclonal Antibody
宿主 Rabbit
别名 ACAD-11
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:15-50.
交叉反应 Human Rat
蛋白分子量 87kDa
Gene ID 84129
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ACAD11
性状 液体
Public Immunogen Range Recombinant protein of human ACAD11
Subcellular Locations Cytoplasm
Swiss Prot Q709F0
克隆类型 Polyclonal Antibody
背景资料 The deduced full-length?ACAD11?protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable?ACAD11?expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11?associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that?ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.