Anti-ACAD11 Polyclonal Antibody
品牌：solarbio | 货号：K008273P
| 英文名称 | Anti-ACAD11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACAD-11 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:15-50. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 87kDa |
| Gene ID | 84129 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ACAD11 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ACAD11 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q709F0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The deduced full-length?ACAD11?protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable?ACAD11?expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11?associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that?ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells. |