Anti-ARC Polyclonal Antibody
品牌：solarbio | 货号：K008318P
| 英文名称 | Anti-ARC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Arg3.1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 23237 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ARC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ARC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q7LC44 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum. |