Anti-PTP4A2 Polyclonal Antibody
品牌：solarbio | 货号：K008224P
| 英文名称 | Anti-PTP4A2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HH13;OV-1;PRL2;HH7-2;PRL-2;PTP4A;HU-PP-1;PTPCAAX2;ptp-IV1a;ptp-IV1b |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 19kDa |
| Gene ID | 8073 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PTP4A2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PTP4A2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q12974 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |