Anti-C8orf4 Polyclonal Antibody
品牌:solarbio | 货号:K004382P
英文名称 |
Anti-C8orf4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
TC-1;TC1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
12kDa |
Gene ID |
56892 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human C8orf4 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human C8orf4 |
Subcellular Locations |
Cytoplasm Nucleus Nucleus speckle nucleolus |
Swiss Prot |
Q9NR00 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. |