Anti-CRYGS Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CRYGS Polyclonal Antibody

品牌:solarbio | 货号:K005531P

英文名称 Anti-CRYGS Polyclonal Antibody
宿主 Rabbit
别名 CRYG8;CTRCT20
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 21kDa
Gene ID 1427
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CRYGS
性状 液体
Public Immunogen Range Recombinant protein of human CRYGS
Subcellular Locations Cytosol Nucleus
Swiss Prot P22914
克隆类型 Polyclonal Antibody
背景资料 Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.