Anti-PTPRE Polyclonal Antibody
品牌:solarbio | 货号:K005089P
英文名称 |
Anti-PTPRE Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HPTPE;PTPE;R-PTP-EPSILON |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
81kDa |
Gene ID |
5791 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PTPRE |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PTPRE |
Subcellular Locations |
Cell membrane Cytoplasm Cytoplasm Single-pass type I membrane protein |
Swiss Prot |
P23469 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. |