Anti-AGR2 Polyclonal Antibody
品牌：solarbio | 货号：K004983P
| 英文名称 | Anti-AGR2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AG-2;AG2;GOB-4;HAG-2;HEL-S-116;HPC8;PDIA17;XAG-2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 20kDa |
| Gene ID | 10551 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AGR2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AGR2 |
| Subcellular Locations | Endoplasmic reticulum Secreted |
| Swiss Prot | O95994 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. |