Anti-TSG101 Polyclonal Antibody
品牌：solarbio | 货号：K006850P
| 英文名称 | Anti-TSG101 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TSG10;VPS23 |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 44kDa |
| Gene ID | 7251 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TSG101 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TSG101 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q99816 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. |