Anti-CNTFR Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CNTFR Polyclonal Antibody

品牌:solarbio | 货号:K003463P

英文名称 Anti-CNTFR Polyclonal Antibody
宿主 Rabbit
别名 CNTFR
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 41kDa
Gene ID 1271
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CNTFR
性状 液体
Public Immunogen Range Recombinant protein of human CNTFR
Subcellular Locations Cell membrane GPI-anchor Lipid-anchor
Swiss Prot P26992
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.