Anti-IL-6R alpha Polyclonal Antibody
品牌：solarbio | 货号：K106877P
| 英文名称 | Anti-IL-6R alpha Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL6R;CD126;IL-6R-1;IL-6RA;IL6Q;IL6RA;IL6RQ;gp80;interleukin 6 receptor |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 52kDa |
| Gene ID | 16194 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL-6R alpha |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL-6R alpha |
| Subcellular Locations | Cell membrane Secreted |
| Swiss Prot | P08887 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |