Anti-MDH1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MDH1 Polyclonal Antibody

品牌:solarbio | 货号:K106619P

英文名称 Anti-MDH1 Polyclonal Antibody
宿主 Rabbit
别名 MDH1;HEL-S-32;MDH-s;MDHA;MGC:1375;MOR2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 36kDa
Gene ID 4190
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MDH1
性状 液体
Public Immunogen Range Recombinant protein of human MDH1
Subcellular Locations Cytoplasm
Swiss Prot P40925
克隆类型 Polyclonal Antibody
背景资料 This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6