Anti-IASPP Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IASPP Polyclonal Antibody

品牌:solarbio | 货号:K106447P

英文名称 Anti-IASPP Polyclonal Antibody
宿主 Rabbit
别名 IASPP;NKIP1;RAI;RAI4
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 120kDa
Gene ID 10848
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human IASPP
性状 液体
Public Immunogen Range A synthetic peptide of human IASPP
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q8WUF5
克隆类型 Polyclonal Antibody
背景资料 Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.