Anti-CXCR4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CXCR4 Polyclonal Antibody

品牌:solarbio | 货号:K106446P

英文名称 Anti-CXCR4 Polyclonal Antibody
宿主 Rabbit
别名 CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 48kDa
Gene ID 7852
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CXCR4
性状 液体
Public Immunogen Range A synthetic peptide of human CXCR4
Subcellular Locations Cell junction Cell membrane Early endosome Late endosome Lysosome Multi-pass membrane protein
Swiss Prot P61073
克隆类型 Polyclonal Antibody
背景资料 Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.