Anti-CXCR4 Polyclonal Antibody
品牌:solarbio | 货号:K106446P
英文名称 |
Anti-CXCR4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
48kDa |
Gene ID |
7852 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CXCR4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CXCR4 |
Subcellular Locations |
Cell junction Cell membrane Early endosome Late endosome Lysosome Multi-pass membrane protein |
Swiss Prot |
P61073 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. |