Anti-MMP13 Polyclonal Antibody
品牌：solarbio | 货号：K106443P
| 英文名称 | Anti-MMP13 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CLG3;MANDP1;MDST |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 58kDa |
| Gene ID | 4322 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MMP13 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MMP13 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | P45452 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. |