Anti-ITA2B Polyclonal Antibody
品牌：solarbio | 货号：K106413P
| 英文名称 | Anti-ITA2B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human |
| 蛋白分子量 | 113kDa |
| Gene ID | 3174 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ITA2B |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ITA2B |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P08514 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |