Anti-DLK1 Polyclonal Antibody
品牌:solarbio | 货号:K008138P
英文名称 |
Anti-DLK1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DLK;FA1;ZOG;pG2;DLK-1;PREF1;Delta1;Pref-1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
41kDa |
Gene ID |
8788 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DLK1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DLK1 |
Subcellular Locations |
Membrane |
Swiss Prot |
P80370 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. |