Anti-CUL7 Polyclonal Antibody
品牌:solarbio | 货号:K008134P
英文名称 |
Anti-CUL7 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
3M1;KIAA0076;dJ20C7.5 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Rat |
蛋白分子量 |
191kDa |
Gene ID |
9820 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CUL7 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CUL7 |
Subcellular Locations |
cytoplasm |
Swiss Prot |
Q14999 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. CUL-7 is highly expressed in fetal kidney and adult skeletal muscle in addition to abundant expression in fetal brain, and adult pancreas, kidney, placenta and heart. It is also detected in trophoblasts, lymphoblasts, osteoblasts, chondrocytes and skin fibroblasts. |