Anti-ANTXR1 Polyclonal Antibody
品牌：solarbio | 货号：K008074P
| 英文名称 | Anti-ANTXR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ATR;TEM8 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 84168 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANTXR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANTXR1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9H6X2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. |