Anti-EID3 Polyclonal Antibody
品牌：solarbio | 货号：K007705P
| 英文名称 | Anti-EID3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NS4EB;NSE4B;NSMCE4B |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 38kDa |
| Gene ID | 493861 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EID3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human EID3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q8N140 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | EID3?is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter. |