Anti-MIDN Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MIDN Polyclonal Antibody

品牌:solarbio | 货号:K007535P

英文名称 Anti-MIDN Polyclonal Antibody
宿主 Rabbit
别名 Midnolin
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 49kDa
Gene ID 90007
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human MIDN
性状 液体
Public Immunogen Range A synthetic peptide of human MIDN
Swiss Prot Q504T8
克隆类型 Polyclonal Antibody
背景资料 Expression of the?midnolin?gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The?midnolin?encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the?midnolin?was studied by using?midnolin-green fluorescent protein (GFP) fusion proteins.?Midnolin?was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the?midnolin.?May be involved in regulation of genes related to neurogenesis in the nucleolus