Anti-CRMP1 Polyclonal Antibody
品牌:solarbio | 货号:K007402P
英文名称 |
Anti-CRMP1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DRP1;DRP-1;CRMP-1;DPYSL1;ULIP-3 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
62kDa |
Gene ID |
1400 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CRMP1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CRMP1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q14194 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Collapsin response mediator protein 1, encoded by the?CRMP1?gene, is a human?protein?of the?CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2. |