Anti-PHLPP1 Polyclonal Antibody
品牌:solarbio | 货号:K007140P
英文名称 |
Anti-PHLPP1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PHLPP1 |
应用 |
IHC |
稀释比例 |
IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
185kDa |
Gene ID |
23239 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PHLPP1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PHLPP1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O60346 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. |