Anti-TAB3 Polyclonal Antibody
品牌:solarbio | 货号:K007097P
| 英文名称 | Anti-TAB3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NAP1;MAP3K7IP3 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 79kDa |
| Gene ID | 257397 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TAB3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TAB3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q8N5C8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.? |