Anti-TAB3 Polyclonal Antibody
品牌:solarbio | 货号:K007097P
英文名称 |
Anti-TAB3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NAP1;MAP3K7IP3 |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
79kDa |
Gene ID |
257397 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TAB3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TAB3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q8N5C8 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.? |