Anti-FBXO32 Polyclonal Antibody
品牌：solarbio | 货号：K006787P
| 英文名称 | Anti-FBXO32 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Fbx32;MAFbx |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 114907 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FBXO32 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FBXO32 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | Q969P5 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |