Anti-CRTAM Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CRTAM Polyclonal Antibody

品牌:solarbio | 货号:K006716P

英文名称 Anti-CRTAM Polyclonal Antibody
宿主 Rabbit
别名 CD355
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 45kDa
Gene ID 56253
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CRTAM
性状 液体
Public Immunogen Range Recombinant protein of human CRTAM
Subcellular Locations cytoplasm
Swiss Prot O95727
克隆类型 Polyclonal Antibody
背景资料 Class-I MHC-restricted T cell associated molecule (CRTAM) is a receptor that is primarily expressed on activated cytotoxic lymphocytes, where it may play a role in their adhesion, interaction or migration. It is one of the most highly expressed surface markers detected on activated human NK T cells and CD8 T cells, suggesting its use as a diagnostic tool in various human viral and autoimmune diseases. CRTAM binds nectin-like protein 2 (necl2), which is involved in IL-22 expression regulation. This Necl2/CRTAM molecular pair may regulate cell/cell interactions and may play a role in neuronal interactions. CRTAM is also highly expressed in Purkinje neurons in the cerebellum.